(Disclaimer: I hadn't seen a definition of profit margins before today, so I have probably no idea what I'm talking about.)
It increasingly seems to me like (profit) margins are worth considering when thinking about career questions and where to work. If your employer has no slack, neither will you.
This was inspired by a (pretty well-made!) video I watched about the visual effects crisis. Per the video, visual effects studios suffer "razor-thin" margins. They also, per the video, sound like exhausting places to work as an artist. This doesn't seem like a coincidence. It seems to line up with what (little) I've read about journalism as well. Maybe other things as well.